Zopiclone (Imovane) is indicated for the short-term remedy and symptomatic aid of insomnia characterized by problem in falling asleep, frequent nocturnal awakenings and/or early morning awakenings.

Treatment with zopiclone should normally not exceed 7-10 consecutive days. Use for greater than 2-3 consecutive weeks requires full re-evaluation of the patient. Prescriptions for zopiclone should be written for short-term use (7-10 days) and it should not be prescribed in quantities exceeding a 1-month provide.

The use of hypnotics should be restricted for insomnia the place disturbed sleep ends in impaired daytime functioning.

Dosage and administration:

Imovane should only be taken when you are able to get a full night time’s sleep (7 to 8 hours) earlier than you should be active once more.
The commonplace adult dose of zopiclone is one tablet simply before you go to bed.
This medication should be taken in a single consumption and not readministered during the same night.
If you might be over sixty five years of age the dose is half a pill taken just before you go to mattress.
If you may have a liver or kidney drawback, the identical old really helpful dose is half a tablet taken simply earlier than you go to bed.

Overdosage:

Signs and signs:

Overdose by zopiclone pills is often manifested by various degrees of central nervous system depression ranging from drowsiness to coma in accordance with the amount ingested. In delicate circumstances, signs include drowsiness, confusion, and lethargy; in additional extreme instances, signs might include ataxia, hypotonia, hypotension, methaemoglobinaemia, respiratory despair, and coma. Overdose should not be life threatening unless mixed with different CNS depressants, including alcohol. Other threat elements, such as the presence of concomitant illness and the debilitated state of the patient, may contribute to the severity of signs and very hardly ever can lead to fatal outcome.

In voluntary or unintended cases of zopiclone overdosage involving doses as a lot as 340 mg, the principal effects reported were prolonged sleep, drowsiness, lethargy and ataxia.

Recommended remedy:

Symptomatic and supportive remedy in enough scientific environment is recommended, attention ought to be paid to respiratory and cardiovascular capabilities. Gastric lavage or activated charcoal is just useful when carried out soon after ingestion.

Hemodialysis is of no value because of the giant quantity of distribution of zopiclone. Flumazenil may be a helpful antidote; however, flumazenil administration may contribute to the appearance of neurological symptoms (agitation, anxiety, convulsionsand emotional lability). Intravenous fluids should be administered as needed.